WebDec 23, 2024 · It has been reported that DGCR5 can regulate the proliferation of lung cancer cells. 11 This study is the first to report the regulatory role of DGCR5 in cancer cell stemness. Therefore, regulating the expression of DGCR5 may serve as a target to treat PC by suppressing cancer stemness. WebDGCR5 correlates with immune checkpoints and immunosuppressive properties. (A, B) Correlation between DGCR5 and immune checkpoints (PD-1, PD-L1, CTLA4, LAG3, TIM-3 and B7-H3) in TCGA and CGGA...
Frontiers LncRNA DGCR5 Isoform-1 Silencing Suppresses the …
WebDec 1, 2024 · A Wnt-Induced lncRNA-DGCR5 Splicing Switch Drives Tumor-Promoting Inflammation in Esophageal Squamous Cell Carcinoma Cell Reports 55 Pages Posted: 1 Dec 2024 Publication Status: Under Review Yue Li Sun Yat-sen University (SYSU) - Department of Experimental Research Boyu Chen Sun Yat-sen University (SYSU) - Department of … WebUsing the median expression level of DGCR5 as a cutoff, patients with high DGCR5 expression had obviously poorer overall survival (OS) than those with low DGCR5 expression (P=0.0159, Figure 1 C ... graphic communcation calstatela
Large-Scale Analysis Reveals the Specific Clinical and Immune …
WebIt was revealed that DGCR5 was highly expressed in PC tissues compared with adjacent normal tissues and was associated with poor prognosis in PC patients. Furthermore, DGCR5 depletion inhibited the proliferation, migration and invasion by increasing apoptosis and inducing G0/G1 cell cycle arrest in vitro. WebLong noncoding RNA (lncRNA) DiGeorge syndrome critical region gene (DGCR5) has been reported to participate in various types of cancers, but its role in GBC remains largely unknown. This study... WebJul 1, 2024 · DGCR5 isoform-1 is localized in cytoplasm and shares the same binding sequence to the tumor-suppressive miR-211-5p with the epithelial-to-mesenchymal … chip white attorney front royal va