Modeling hematopoietic disorders in zebrafish
Webin this issue of Disease Models & Mechanisms demonstrates that zebrafish can also be a useful model for studying the role of these innate immune sensors (Oehlers et al., 2011). Over the last 20 years, the zebrafish has risen to prominence as a bona fide research model and has proven to be an excellent vertebrate system for immunology studies. Web1 okt. 2010 · Modeling of several types of this disorder in zebrafish has recently been described. Polycythemia rubra vera Over 90% of polycythemia rubra vera cases are …
Modeling hematopoietic disorders in zebrafish
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WebSilica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro Junchao Duan,1,2 Shuang Liang,1,2 Lin Feng,1,2 Yang Yu,1,2 Zhiwei Sun1,2 1Department of Toxicology and Sanitary ... Sun Z. Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model. Biomaterials. 2013;34(23):5853–5862 ... Web30 mrt. 2024 · Zebrafish embryos transgenically expressing the equivalent mutations in the context of the zebrafish CXCR4 equivalent, Cxcr4b, possessed reduced numbers of …
WebHealth innovation project manager, PhD in Bioengineering, with practice in different contexts - clinics, academy and industry. Research experience focused in metabolism, specifically on the proteomic analysis of gut-derived extracellular vesicles in prediabetes. PhD project resulted of a sucessfull collaboration between Instituto Superior Técnico de Lisboa, … Web11 apr. 2024 · Type I diabetes is a prominent human pathology with increasing incidence in the population; however, its cause is still unknown. This disease promotes detrimental effects on reproduction, such as lower sperm motility and DNA integrity. Hence, the investigation of the underlying mechanisms of this metabolic disturbance in reproduction …
WebNewell Hall, Room 202 1700 Stadium Road PO Box 117535 Gainesville, FL 32611 +1 (352) 846-3222 [email protected] WebRecently, thalidomide and its immunomodulatory derivatives (IMiDs) lenalidomide and pomalidomide, have been used for the treatment of multiple myeloma (MM) and other hematologic malignancies. Other thalidomide analogs, now known as the Cereblon E3 ligase modulators (CELMoDs), including CC-122, CC-220 and CC-885, have been …
Web30 mrt. 2024 · To study human disease-causing variants, researchers have established genetic zebrafish models by utilizing random chemical mutagenesis [using N-ethyl-N …
Web28 mrt. 2015 · Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides … industrial language in the workplaceWeb18 jul. 2024 · Zebrafish as a model for leukemia and other hematopoietic disorders. J. Hematol. Oncol. 8, 29. 10.1186/s13045-015-0126-4 [Europe PMC free article] [Google … logia firmware downloadWebIn both models, PTN increased survival by accelerating the recovery of BM hematopoietic stem and progenitor cells in vivo. PTN treatment promoted HSC regeneration via activation of the RAS pathway in mice that expressed protein tyrosine phosphatase receptor-zeta (PTPRZ), whereas PTN treatment did not induce RAS signaling in PTPRZ-deficient mice ... logi 1080p webcam software windows 11Web12 okt. 2015 · In this study, we cloned the full-length cDNA of E-selectin of zebrafish (Danio rerio), analyzed its expression pattern and preliminarily explored its biological function. Zebrafish E-selectin cDNA is 3146 bp and encodes a putative 871 amino acid protein. All structural domains involved in E-selectin function are conserved in the putative protein. … logia earth株式会社WebIntroduction: We previously identified somatic activating mutations in the KRAS gene in the endothelium of the majority of human sporadic brain arteriovenous malformations (bAVMs); a disorder... industrial large wall clocksWebJonathan Baell PhD is a highly experienced and well-credentialed medicinal chemist, & Executive Director of Early Leads Chemistry at Lyterian Therapeutics (San Francisco). He is a Distinguished Visiting Professor at Nanjing Tech University, and a sought-after Medicinal Chemistry Consultant. From 2012-2024, he has been Director, Australian Translational … logi 4k webcam softwareWebContact Creative Biolabs to Customize CD45 Antibody, which reacts with Dog (Canis lupus familiaris). This product is a mouse antibody against CD45. It can be used for CD45 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. logi 720p instructions