Gc1qr antibody
WebThis GC1qR (C1QBP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the C-terminal region of human GC1qR (C1QBP). Dilution : WB~~1:1000: Format : Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated … WebTherefore, blockade of gC1qR by inhibitory peptides or antibodies may not only prevent the generation of BK but also reduce Clq-induced or microbial-ligand-induced inflammatory responses. Employing synthetic peptides and gClqR deletion mutants, we confirmed previously predicted sites for C1q (residues 75-96) and HK (residues 204-218) and ...
Gc1qr antibody
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WebMar 15, 2002 · To identify relative positions of the cleavage fragments within the gC1qR molecule, we used Western blotting with mAb 60.11 directed to the N-terminal portion of gC1qR. This antibody recognized the 12- and 11-kDa cleavage fragments but failed to interact with the 17-kDa fragment of gC1qR (Fig. 3). These data indicated that the MT1 … WebFeb 18, 2011 · It has been previously reported that a mitochondrial/cell surface protein, p32/gC1qR, is the receptor for a tumor-homing peptide, LyP-1, which specifically recognizes an epitope in tumor cells, tumor lymphatics, and tumor-associated macrophages/myeloid cells. Using antibody phage technology, we have generated an anti-p32 human …
WebResults of immunohistochemical staining of selected normal epithelial and mesenchymal tissue for gC1qR with monoclonal antibody 60.11. gC1qR expression is represented by brown staining. Note gC1qR staining of epithelium of breast and prostate, colonic mucosal glands, hepatocytes and liver bile duct, bronchial epithelium and submucosal glands of ... WebJun 24, 2016 · Antibody neutralization of gC1qR prevents cell migration. A and B. A549, MDA-MB-231, MCF7 and HeLa cells were serum-starved for 18 h and pretreated with 10 μg/mL of mock IgG or anti-gC1qR ...
WebOct 6, 2024 · gC1qR is highly expressed in breast cancer and plays a role in cancer cell proliferation. This study explored therapy with gC1qR monoclonal antibody 60.11, …
WebFeb 3, 2009 · Cellular and mitochondrial proteins were isolated from cells infected with Sendai virus and immunoblotted, using a monoclonal antibody for gC1qR or a Myc antibody. Endogenous gC1qR levels clearly increased in the mitochondrial fraction upon viral infection, whereas total cellular levels of gC1qR remained the same ( Fig. 2 F ).
WebApr 9, 2024 · Transient Antibody Production; Stable Cell Line Antibody Production; Humanized Ab. CDR Grafting; Nanobody; Assay Development. Immunohistochemistry; Antibody Pair; Proteoscreen® Tissue Profiling; Companion Diagnostics; FISH Probes; mutaFISH™ Probes; ELISA Kits; Neutralizing Antibody Assay; Tumor Animal Models. … steam workshop ets 2WebBK induces its activity via two G protein-coupled receptors: BK receptor 1 (B1R) and BK receptor 2. Although BK receptor 2 is constitutively expressed on endothelial cells (ECs), B1R is induced by IL-1β. The C1q receptor, receptor for the globular heads of C1q (gC1qR), which plays a role in BK generation, is expressed on activated ECs and is ... pink floyd animals sacd reviewWebSep 7, 2024 · Therefore, in this study, the inhibitory role of anti-gC1qR monoclonal antibody 74.5.2 in HK binding to endothelial cells was investigated. We hypothesized … pink floyd animals new releaseWeb犬圆环病毒(CanineCV)是近年被发现的圆环病毒属新成员,获取CaineCV Cap蛋白,为研究Cap蛋白的功能以及抗原表位奠定了基础。本研究以CaineCV GX2024株基因组作为模板,使用PCR方法扩增出Cap蛋白的基因序列,对其进行生物信息学分析,并克隆至pET-28a原,进行原核表达。结果表明:GX2024的N端2~26位氨基酸存在一个核定 ... steam workshop errorWebThis antibody recognizes p32. The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. steam workshop fable anniversaryWebOct 6, 2024 · gC1qR is highly expressed in breast cancer and plays a role in cancer cell proliferation. This study explored therapy with gC1qR monoclonal antibody 60.11, directed against the C1q binding domain of gC1qR, in a murine orthotopic xenotransplant model of triple negative breast cancer. MDA231 breast ca … steam workshop downloader – gramvioWebMouse monoclonal GC1q R antibody [60.11]. Validated in WB, IHC, ICC, Flow Cyt and tested in Human. Cited in 21 publication(s). Independently reviewed in 3 review(s). ... GC1QR antibody; globular domain of, C1q, receptor for antibody; Glycoprotein … pink floyd animals release date